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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Tryptophan operon leader ： ウィキペディア英語版 Tryptophan operon leader The Tryptophan operon leader is an RNA element found at the 5' of some bacterial tryptophan operons. The leader sequence can assume two different secondary structures known as the terminator and the anti-terminator structure. The leader also codes for very short peptide sequence that is rich in tryptophan. The terminator structure is recognised as a termination signal for RNA polymerase and the operon is not transcribed. This structure forms when the cell has an excess of tryptophan and ribosome movement over the leader transcript is not impeded. When there is a deficiency of the charged tryptophanyl tRNA the ribosome translating the leader peptide stalls and the antiterminator structure can form. This allows RNA polymerase to transcribe the operon. At least 6 different amino acid operons are known to be regulated by this attenuation. ==Trp RNA-binding attenuation protein== The formation of the anti-terminator requires the trp RNA-binding attenuation protein (TRAP protein) in species of ''Bacillus'' and related bacteria. This protein is encoded by the MtrB gene.〔 〕 TRAP protein forms an oligomer of 11 subunits, in the presence of tryptophan this binds to section of RNA containing 11 (G/U)AG repeats. This sequence overlaps the anti-terminator loop, thus TRAP-binding preventing formation of the anti-termintor loop. When TRAP is bound the termintor loop forms and the operon is not transcribed.〔 〕〔 〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Tryptophan operon leader」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.